January is Glaucoma Awareness Month

 

Glaucoma is a leading cause of vision loss and blindness in the United States. Glaucoma has no early symptoms — that’s why half of people with glaucoma don’t know they have it. 

The only way to find out if you have glaucoma is to get a comprehensive dilated eye exam. There’s no cure for glaucoma, but early treatment can often stop the damage and protect your vision.   

Anyone can get glaucoma, but those at higher risk include: 

  • Everyone over age 60, especially Hispanics/Latinos 
  • African Americans over age 40 
  • People with a family history of glaucoma 

National Glaucoma Awareness month is important because:

  1. It’s a silent disease – Open-angle glaucoma, the most common type, has no symptoms. Without treatment, those affected will slowly lose their peripheral vision. If glaucoma remains untreated, people may miss objects to the side and out of the corner of their eye.
     
  2. It gives others a voice – National Glaucoma Awareness Month helps patients cope. It’s a time to let them share their stories.
     
  3. It’s important to spread the word – The main objective of this month is to keep people in the know about this disease. Not everyone is aware of how easily they can be affected. Eye care organizations use this month to address the risks and provide treatment tips.

 

Questions for your doctor

If you or a loved one has been diagnosed with glaucoma, you may have lots of questions. Starting treatment early is the best way to stop the damage and protect your vision. Talk to your eye doctor about your symptoms and treatment options.  

Here are a few questions to ask your doctor:

  • What type of glaucoma do I have?
  • How often do I need to get a checkup for my glaucoma?
  • What are my treatment options?
  • What will happen if I don’t get treated for my glaucoma?
  • How will I know if my treatment is working?
  • What are the possible dangers or side effects from treatment?
  • Is there anything I can do to prevent my glaucoma from worsening?
  • Does glaucoma put me at risk for other eye diseases?
  • What can I expect for my vision — now and in the future?
  • Are there any activities I should avoid?

Visiting the doctor can be stressful, especially when you’re dealing with a new diagnosis. It helps to have questions written down ahead of time. 

 

Discovery Eye Foundation is currently funding research to find better treatments for glaucoma. Gifts of any size can make a difference.

Donate Today!

 

Glaucoma simulation video courtesy of NEI

 

 

 

Happy New Year

Thank You to all who helped support Sight-Saving Research this year!

 Discovery Eye Foundation has been successful in 2021 and all because of very loyal and dedicated donors that continue to support sight-saving research.

  We are thankful for every gift you have given to the Discovery Eye Foundation.

Wishing you and yours a Healthy and Happy 2022!!! 

You Can Teach an Old Drug New Tricks

Previously Approved Drug Shows Promise for Dry Age-Related Macular Degeneration (AMD)

Getting FDA approval for new treatments can take years or even decades. But what about repurposing drugs that have already been approved for other diseases? That’s precisely the question DEF-supported researchers are asking about a new treatment for dry age-related macular degeneration (AMD) and other aging diseases, including Alzheimer’s and Parkinson’s.

Six years ago, DEF Research Director Dr. Cristina Kenney began collaborating with Parkinson’s specialist Dr. Howard Federoff of the Department of Neurology at UC Irvine. DEF-supported researchers had previously shown that damaged mitochondria are a significant factor in accelerating cell death in AMD, and Kenney developed a cybrid mitochondria model to study AMD. Federoff had set up a screening system to look at drugs previously approved by the FDA that might improve the health of mitochondria, whose demise also contribute to Parkinson’s and Alzheimer’s. Of more than a thousand drugs screened, he identified 13 that could rejuvenate mitochondria. Kenney’s cell-culture models and Federoff’s system were a match made in research heaven.

Together, the researchers homed in on one drug, which Federoff named PU-91, because it was the 91st drug he’d tested. “When we added PU-91 to our AMD cybrids, the cells lived longer, they functioned better   the damage to the mitochondria was decreased and it really improved the health of the mitochondria,” Kenney says. “PU-91 is a drug called fenofibrate, which has been used for years to treat high cholesterol. When this drug is modified slightly, it helps sluggish mitochondria regain their health. We’re taking a drug that has been used for many years with FDA approval, and we’re repurposing it for a new target and new types of diseases.”

Benefits of Repurposing

After treatment with PU-91, the AMD mitochondria are greatly increased in number and are healthier (green dye). Blue stains nucleus of cells.

Tremendous savings of time and money are to be had by repurposing a known drug rather than starting with a drug people have never used before. Perhaps most importantly, because it’s been used for so many years in patients, the known drug has a proven safety track record. PU-91 has an additional advantage in that it is taken orally. While there is currently one type of treatment for wet AMD — an injection — there is no treatment at all for the dry form of AMD. An oral treatment for dry AMD is a game-changer.

The research is going so well that a company has been formed specifically to bring this drug to market for dry AMD. “As we become more successful, this type of drug can also be used for neurodegenerative diseases that have damaged mitochondria, such as Parkinson’s disease and Alzheimer’s disease,” Kenney says. “Potentially, it might even be used for something, such as glaucoma, that causes cell death of the retina ganglion cells in the eye. There are a lot of potential uses for it.”

Bench to Bedside

DEF currently is supporting ongoing studies to optimize PU-91’s formulations for maximum effectiveness in patients with AMD. “It’s exciting, because this is the goal for translational researchers,” Kenney says. “Take what you’re doing at the bench and bring it to the bedside.”

If you would like to support our sight saving research click here, DONATE NOW

Beware of Costume Contacts this Halloween

Costume Contact Lenses such as cat eyes or zombie may make your Halloween costume a bit more frightful although wearing those lenses without a prescription can be more terrifying, as it could result in vision loss or even blindness.

You can buy contact lenses, including decorative contact lenses, from your eye doctor or on the Internet.  It’s very important that you only buy contact lenses from a company that sells FDA-cleared or approved contact lenses and requires you to provide a prescription.  Even if you don’t wear corrective lenses you still need to get fitted properly.

Remember — Buying contact lenses without a prescription is dangerous!

Right now there are a lot of products that you can buy without a prescription but they may not be safe or legal.

You should NEVER buy lenses from:

  • street vendors
  • salons or beauty supply stores
  • boutiques
  • flea markets
  • novelty stores
  • Halloween stores
  • convenience stores
  • beach shops
  • internet sites that do not require a prescription

Know the Risks –

Wearing costume contact lenses can be risky, just like the contact lenses that correct your vision. Wearing any kind of contact lenses, including costume lenses, can cause serious damage to your eyes if the lenses are obtained without a prescription or not used correctly.

These risks include:

  • A cut or scratch on the top layer of your eyeball (Corneal Abrasion)
  • Allergic reactions like itchy, watery red eyes
  • Decreased vision
  • Infection
  • Blindness

Signs of possible eye infection:

  • Redness
  • Pain in the eye(s) that doesn’t go away after a short period of time
  • Decreased vision

If you have any of these signs, you need to see a licensed eye doctor (optometrist or ophthalmologist) right away!  An eye infection could become serious and cause you to become blind if it is not treated.

This Halloween season DEF wants to remind you of the importance of eye safety and to make sure to take the proper steps in ensuring the proper contact lenses. 

Tips To Protect Children From Digital Eye Strain

With COVID-19 and a shift to online learning by many schools, children are spending even more time looking at screens. Staring at digital screens for a long period of time can cause hazy, blurred vision and can make eyes burn and feel dry, itchy and irritated. This condition is known as digital eye strain or computer vision syndrome. Other symptoms of digital eye strain can include:

  • Neck and shoulder pain
  • Headaches
  • Fatigue
  • Words moving on the screen (due to underlying eye alignment issues)

What Parents Can Do:

  • Monitor screen time. Find some balance between the digital and real world. Two especially important aspects of this are making sure screens don’t cut into:
    • Sleep. Not getting enough shut-eye leads to tired, sore eyes. Avoid exposure to screens for 1 hour before going to bed. Using devices past bedtime, especially for violent video games or shows, can interfere with sleep.
  • Putting down the device or stepping away from the computer or TV can help avoid eye and vision problems from too much screen time. Children age 6 years and older should be getting at least 60 minutes of physical activity each day. Active play is the best exercise for young children. Outside play can also be a great “workout” for children’s vision—giving them a chance to focus at different distances and getting exposure to natural sunlight.
  • Take frequent breaks. Children frequently get so absorbed in what they’re doing that they don’t notice symptoms of eye strain. Remind them to take breaks. Use the 20/20/20 rule: look away from the screen every 20 minutes, focus on an object at least 20 feet away, for at least 20 seconds. In addition, children should walk away from the screen for at least 10 minutes every hour. A simple timer can help your child remember, and there are even software programs that can help by turning off the screen in regular intervals.

  • Remember to blink. Staring at a computer can cut blinking rates by half and cause dry eyes. Encourage your child to try to blink extra, especially when they take breaks. Your pediatrician or eye doctor may recommend moisturizing eye drops or a room humidifier if your child continues to be bothered by dry eyes.
  • Screen positioning. Make sure the screen on your child’s desktop or laptop computer is slightly below eye level. Looking up at a screen opens eyes wider and dries them out quicker. Some experts suggest positioning device screens based on the 1/2/10 rule: mobile phones ideally at one foot, desktop devices and laptops at two feet, and roughly 10 feet for TV screens (depending on how big the screen is). Adjusting the font size—especially on smaller screens—so it’s twice as big as your child can comfortably read may also help reduce eye fatigue.
  • Spotlight on lighting. To cut down on glare and eye fatigue, consider the level of lighting in a room when using a computer or other screen. Ideally, it should be roughly half what it would be for other activities such as writing on paper or working on crafts. Try to position computers so that light from uncovered windows, lamps and overhead light fixtures aren’t shining directly on screens. Decrease the brightness of the screen to a more comfortable level for viewing. Some optometrists recommend special computer glasses with orange lenses that may also help reduce glare. Children who wear prescription eyeglasses may have an anti-reflective coating added, as well.
  • Get regular vision screenings. If your child is having blurry vision or similar eye problems, he or she may not speak up. That’s why regular vision screenings are important. The American Academy of Ophthalmology recommend children have their eyes checked by a pediatrician at well-child visits beginning at birth. If a problem is found during one of these routine eye exams, your pediatrician may refer you to a pediatric ophthalmologist.

Children, especially younger ones, will likely need help and reminders to use digital screen devices in an eye-friendly way.  If you have any questions about keeping your child’s eyes and vision healthy, talk with your pediatrician.

Eye Care Tips for Travelers

Proper eye care is one of the most essential aspects people tend to ignore during, or when planning their travel. The following tips might help you in keeping your eyes healthy when traveling:

1.    Pack accordingly

Pack the following:

    • Lubricating eye drops: Consider packing allergy-specific eye drops that are specially formulated for allergies.
    • Eye wash solution: If you have something in your eye — an eyelash, a fleck of dust — you might be tempted to head to the nearest restroom to wash out your eye with tap water. Stop. That tap water could contain impurities or minerals which may further irritate your eyes or cause an infection. Use a sterile eye wash instead—purchased at your drugstore.
    • Sunglasses and a hat – Goggles if you plan to go swimming
    • Sleep mask

2.   Don’t wear contacts for long-haul trips.

If you’re about to take a long road trip or get on a plane, play it safe by opting for glasses from the start.  Make sure to aim air vents away from your eyes, constant temperature fluctuations and lack of humidity could irritate your eyes.

3.    Apply a warm compress at the end of each leg of the trip

Once you reach your destination, wet a washcloth with warm water and drape it over your eyes for 5-10 minutes. If your eyes feel like they have something in them, try an eye wash solution to irrigate your eyes.

4.   Take steps to manage eye strain.

Eye strain is common, and when you’re a tired traveler, it could get the best of you. The best ways to manage eye strain include limiting screen time and adjusting your lighting, so whether you’re working on your computer or watching in-flight movies, be sure to take frequent breaks. A simple approach is the 20-20-20 rule: Every 20 minutes look away from your screen for 20 seconds and focus on something 20 feet away.

5.    Invest in good sunglasses and wear them

Sunglasses help you avoid glare and air borne foreign particles. They also protect from UV rays. According to the American Academy of Ophthalmology, you should buy glasses that are 100% UV-resistant.  The term “polarized” means they cut glare, not UV rays. AAO recommends buying sunglasses that are large to provide optimal coverage.

Tips for beating dry eyes when traveling

  • Eat a healthy diet of foods that nourish your eyes like Omega 3s and foods rich in Vitamin A. Always make sure you drink plenty of water throughout the day, as this will ensure you stay hydrated.
  • Always make sure you are taking proper care of your contact lenses and putting them in correctly.
  • Wear glasses on a windy day to protect your eyes from becoming dry or irritated. You should also make sure your sunglasses are polarized and filter out 100% of harmful UV rays and block harsh glare off of different surfaces.
  • Avoid areas where there is lots of smoke from fires or cigarettes, as smoke can irritate and make dry eyes feel sore.
  • Make sure you pack lubricating eye drops and medicated eye drops if you require them so that you can treat your eyes immediately when they begin to feel dry. Some users recommend Bausch & Lomb anti-red drops, Lumify.
  • Pack oral allergy medication that will combat any allergies to new pollens or allergens.

These tips will help you take good care of your eyes while traveling.

DEF-Funded Retinitis Pigmentosa(RP) and Age-Related Macular Degeneration(AMD) Projects Converge with Promise

Two hallmark DEF-funded projects are converging, providing great hope for those facing vision loss from retinitis pigmentosa (RP) or age-related macular degeneration (AMD).

The first project, headed by UC Irvine researchers Drs. Henry Klassen and Jing Yang, concentrates on putting human retinal progenitor cells into the eyes of those with RP in order to rescue damaged retinal cells. That project is currently in Phase II clinical trials, progressing toward FDA approval.

                                                      Tissue-culture model

According to DEF Research Director Dr. Cristina Kenney, if the project is approved by the FDA for use with RP, the next question is: What other diseases might these retinal progenitor cells be used for? That’s where a second DEF-funded project comes in.

Kenney is working on a “personalized” cybrid cell model to screen agents that specifically target the mitochondria in AMD cells. To date, the researchers have different cybrid cell lines representing 60 different individuals with eye diseases. They are looking for novel mechanisms to protect AMD cells from dying.

Yang and Kenney are now working together to determine whether the retinal progenitor cells can be the agent that rescues AMD cybrids. “When we take the mitochondria from AMD patients and put them into healthy retinal cells, which makes cybrids, we have shown that these AMD cybrid cells will start to die. So we used that model to ask the question: How do we rescue them?” Kenney says.

Kenney and Yang developed a tissue culture model, where the retinal progenitor cells are grown in one part of a chamber, and the AMD cybrids are grown in another part of chamber, surrounded by culture medium. There is a porous separator between the two chambers through which the cells can communicate.

 “We are finding that the retinal progenitor cells produce a factor that protects the AMD cybrids,” Kenney says. “This provides promising evidence that these proprietary retinal progenitor cells that are being tested for treating RP also may be helpful in AMD patients.”

“DEF has been supporting both these retina-related projects for quite some time, and it’s very exciting to see them coming together to potentially treat both RP and AMD.”

To help support this sight-saving research, please donate to the Discovery Eye Foundation by clicking button below.

July is UV Safety Awareness Month

According to the American Academy of Ophthalmology, studies show that long-term exposure to bright sunlight may increase the risk of cataracts and growths on the eye, including cancer.

UV rays reflected off sand and water can cause eyes to sunburn, potentially resulting in temporary blindness in just a few hours. In support of UV Safety Month this July, the American Academy of Ophthalmology reminds the public of the importance of shielding eyes from the sun’s harmful rays with 100% UV-blocking sunglasses and broad-brimmed hats.

Here are some tips from the American Academy of Ophthalmology:

  • Don’t focus on color or darkness of sunglass lenses: Select sunglasses that block UV rays. Don’t be deceived by color or cost. The ability to block UV light is not dependent on the price tag or how dark the sunglass lenses are.
  • Check for 100 percent UV protection: Make sure your sunglasses block 100 percent of UV-A rays and UV-B rays.
  • Choose wrap-around styles: Ideally, your sunglasses, either the lenses of the frame, should wrap all the way around to your temples, so the sun’s rays can’t enter from the side.
  • Wear a hat: In addition to your sunglasses, wear a broad-brimmed hat to protect your eyes.
  • Don’t rely on contact lenses: Even if you wear contact lenses with UV protection, remember your sunglasses.

  • Don’t be fooled by clouds: The sun’s rays can pass through haze and thin clouds. Sun damage to eyes can occur anytime during the year, not just in the summertime.
  • Protect your eyes during peak sun times: Sunglasses should be worn whenever outside, and it’s especially important to wear sunglasses in the early afternoon and at higher altitudes, where UV light is more intense.
  • Never look directly at the sun. Looking directly at the sun at any time, including during an eclipse, can lead to solar retinopathy, damage to the eye’s retina from solar radiation.
  • Don’t forget the kids: Everyone is at risk, including children.
  • Protect their eyes with hats and sunglasses. In addition, if possible, try to keep children out of the sun between 10 a.m. and 2 p.m., when the sun’s UV rays are the strongest.

In addition to the proper safety eyewear, regular eye exams for early detection and treatment of eye conditions and diseases are essential to maintaining good vision at every stage of life.

According to the American Academy of Ophthalmology, children with a family history of childhood vision problems should be screened for common childhood eye problems before the age of 5. If eye problems such as visual changes, pain, flashes of light, seeing spots, excessive tearing and excessive dryness occur, they should see an eye doctor. Adults between the ages of 40 to 65 should have an eye exam every two years. Adults over the age of 65 should have an eye exam at least every one to two years.

 

April is Women’s Eye Health Month

This month of April is dedicated to

WOMEN’S EYE HEALTH MONTH

With Women’s History Month, Women’s Eye Health Month and Mother’s Day all happening this spring, we’ve got all of the women in our lives on our minds. 

Did you know that blindness affects women more than men? The National Institutes of Health reports that 2/3rds of the people with blindness or visual impairments are women.  Often, hormones, and especially life changes such as pregnancy and menopause, cause changes in women’s eyes.  Preventing blindness and vision problems requires keeping a healthy lifestyle, avoiding certain habits, and seeing the eye doctor regularly.

Many women aren’t aware that they have a higher risk for developing eye and vision problems.  In an effort to create awareness of various eye diseases that women are more prone to have than men, April has been dedicated to educating women about these diseases, along with providing resources and recommendations on the best ways to maintain excellent vision for women.

The National Eye Institute also stated that women deal with greater instances of eye disorders, in part, because they tend to live longer than men, are more likely to undergo cancer treatments which affect vision, and experience age-related hormonal changes that can affect the eyes. Women also have higher rates of eye diseases such as cataract, glaucoma, and age-related macular degeneration than men.

As we mentioned, hormones are a factor in developing eye problems, but also lifestyle, genetics, pregnancy and more contribute to the problems. Women pass through several biological and hormone changes that men do not. Pregnancy causes changes in the eyes such as dry eyes, puffiness, migraine headaches that affect vision, light sensitivity and more. If a woman is not pregnant, even taking birth control can cause hormonal changes and blood clots in some cases. If a clot happens, that can lead to strokes that affect vision, sometimes permanently.

Later in life, eye problems become more frequent in both men and women. However, women statistically have a higher chance of developing chronic conditions such as lupus, arthritis, multiple sclerosis and more. All of these conditions can affect eye health.

It’s important for women to know the risks for eye-related diseases resulting in vision impairment and take the steps to prevent eventual vision loss.  Here are some ways that you can help to protect your eyes and save your eyesight:

  • Find out about your family history of eye diseases and conditions.
  • Protect your eyes from the sun by wearing 100% UV blocking sunglasses when outdoors.
  • Don’t smoke.
  • Consume a healthy diet with proper nutrition and special eye health supplements as prescribed by an eye doctor. (Eye Healthy Recipes)
  • Adhere to contact lens hygiene and safety.
  • Adhere to cosmetic hygiene and safety precautions.
  • Protect your eyes against extended exposure to blue light from computers, smartphones and LED lamps.
  • If you are pregnant or planning to become pregnant and have diabetes, see an eye doctor for a comprehensive eye exam. In women who have diabetes, diabetic retinopathy can accelerate quickly during pregnancy and can present a risk for the baby as well.

Mothers are often charged with caring for the eye health of the entire family, but too often their own eye health is neglected.  It is critical that mothers take care of their eyes and overall health so that they can be in the best condition to care for their families.

Speak to your eye care professional about your personal eye health and vision risks so you can exercise the precautions and measures to protect your eyes.   Encourage the other women in your life to do so as well.  Once vision is lost, it often cannot be regained and there are many steps you can take to prevent it with proper knowledge and awareness.

The most important way to prevent vision loss is to ensure you schedule regular eye exams. Don’t wait for symptoms to appear as many eye issues are painless and symptomless, and sometimes by the time you notice symptoms, vision loss is untreatable.

Click here for Eye Healthy Recipes.

 

How to Prevent Eye Strain While Working From Home

Working from home has become the new normal for many Americans during this pandemic.  Most are happy without the commute, although working outside the office and in all sorts of strange places, such as bedrooms, backyards, living rooms, has become common place. We’ve had to learn how to work remotely, which in turn means spending a lot more time using computers and smartphones.

Moving out of properly-lit classrooms and offices – and away from ergonomically correct desks – can have long-term effects on our eyes.  Excessive time at a computer screen under the best conditions can lead to symptoms of eye strain.

Eye Strain Symptoms include:

  • Headaches
  • Blurred vision
  • Uncomfortable dry eyes
  • Neck and shoulder pain

To help avoid eye strain, here are few tips for working from home:

  • Record time spent on screens – Most adults age 18 and older spend at least 13 hours each day using digital devices. Extended screen time can cause discomfort and vision difficulties. When working from home, you may lose track of how much time you’re on your computer or smartphone.  So keep track of the hours you use devices. That way, you’ll be aware of the demand you’re placing on your eyes.
  • Rest and blink your eyes – Researchers found that over 30% of people using digital devices rarely take time to rest their eyes. Just over 10% say they never take a break, even when working from home. The eye muscles get overworked and don’t get a chance to relax and recover. Experts suggest the 20-20-20 rule; every 20 minutes, focus your eyes and attention on something 20 feet away for 20 seconds.  You can also get up and walk around for a few minutes.

 

  • Reduce exposure to blue light – In the spectrum of light, blue is more high energy and close to ultraviolet light. So, if you use screens throughout the day, ask your eye doctor about the value of computer glasses that block blue light. Reducing exposure to blue light may help lessen vision problems.  At home, using digital devices until bedtime can overstimulate your brain and make it more difficult to fall asleep. Eye doctors recommend no screen time at least one to two hours before going to sleep.

  

  • Sit up straight – Proper posture is important. Your back should be straight and your feet on the floor while you work. Elevate your wrists slightly instead of resting them on the keyboard.

 

 

  • Proper lighting – A setting that’s too bright (sunny backyard) or too dim (cavernous basement) can cause eye strain and headaches. Your screen should be bright enough that you don’t need to squint. A screen shield can help reduce glare.

 

  • Set up monitor properly – Make sure your computer screen is about 25 inches, or an arm’s length, away from your face. The center of the screen should be about 10-15 degrees below eye level.  Cut glare by using a matte screen filter. You can find them for all types of computers, phones, and tablets.  Increase font size or set the magnification of the documents you are reading to a comfortable size.

 

  • Consider computer glasses –For the greatest comfort at your computer, you might benefit from having your eye doctor modify your eyeglasses prescription to create customized computer glasses. This is especially true if you normally wear distance contact lenses, which may also become dry and uncomfortable during extended screen time.  Computer glasses also are a good choice if you wear bifocals or progressive lenses, because these lenses generally are not optimal for the distance to your computer screen.
  • Create Technology-Free Zones – These tips can help reduce eye strain when you’re forced to look at screens all day, creating technology-free zones in certain areas of your home, like the bedroom or bathroom. If you spend the entire day working on the computer, getting in bed and scrolling through social media until you fall asleep won’t do your eyes any favors.

Once you’re done for the day, truly unplug. Read a book or spend some quality time with family members without your phone.

 

  • Get an Eye Exam – If you have tried all these tips and eye strain is still an issue, it might be time to see an eye care professional to schedule an eye exam.  The exam may even detect underlying issues before they becomes worse.